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  • Autoencoders for Single Cell Data Analysis

    calendar Jan 5, 2026 · 48 min read · AI Deep Learning dimensional reduction single cell RNAseq  ·
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    Autoencoders for Single Cell Data Analysis

    Explore the use of autoencoders to compress gene expression data and improve data analysis and visualization.


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  • BiocPy: Bioconductor in Python

    calendar Nov 25, 2025 · 8 min read · Bioconductor single cell  ·
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    BiocPy: Bioconductor in Python

    A quick tour of biocpy, the first Python framework to deliver Bioconductor-style data structures and workflows for genomic data analysis.


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  • Bringing the Tidyverse to Python: plotnine, siuba, and pyjanitor

    calendar Nov 23, 2025 · 7 min read · code Plots  ·
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    Bringing the Tidyverse to Python: plotnine, siuba, and pyjanitor

    Learn how to implement a tidy and expressive R-like data analysis pipeline in Python, complete with dplyr-style transformations and ggplot-style plots.


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  • Use uv for python and forget about anything else!

    calendar Oct 14, 2025 · 5 min read · uv  ·
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    Use uv for python and forget about anything else!

    Replace pip & virtualenvwrapper with uv for instant, reproducible Python environments.


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  • Building Your First Nextflow Pipeline: PART 4 - Polish your pipeline

    calendar Aug 31, 2025 · 8 min read · code single cell pseudoalignment RNAseq  ·
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    Building Your First Nextflow Pipeline: PART 4 - Polish your pipeline

    Learn how to build bioinformatics pipelines with Nextflow, a powerful workflow management system for reproducible and scalable data analysis. PART 4 - Polish your pipeline


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  • Building Your First Nextflow Pipeline: PART 3 - Modularization & Configurable settings

    calendar Aug 30, 2025 · 5 min read · code single cell pseudoalignment RNAseq  ·
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    Building Your First Nextflow Pipeline: PART 3 - Modularization & Configurable settings

    Learn how to build bioinformatics pipelines with Nextflow, a powerful workflow management system for reproducible and scalable data analysis. PART 3 - Modularization & Configurable settings


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  • Building Your First Nextflow Pipeline: PART 2 - Multiple Samples

    calendar Aug 27, 2025 · 9 min read · code single cell pseudoalignment RNAseq  ·
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    Building Your First Nextflow Pipeline: PART 2 - Multiple Samples

    Learn how to build bioinformatics pipelines with Nextflow, a powerful workflow management system for reproducible and scalable data analysis. PART 2 - Multiple Samples


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  • Alignment or Pseudoalignment: Alevin-fry vs Cell Ranger comparison

    calendar Aug 6, 2025 · 9 min read · Bioconductor code single cell RNAseq  ·
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    Alignment or Pseudoalignment: Alevin-fry vs Cell Ranger comparison

    Compare Alevin-fry’s pseudoalignment and Cell Ranger’s full alignment to find the right single-cell RNA-seq tool for your pipeline.


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  • Building Your First Nextflow Pipeline: PART 1 - One sample at a time

    calendar Jul 30, 2025 · 8 min read · code single cell pseudoalignment RNAseq  ·
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    Building Your First Nextflow Pipeline: PART 1 - One sample at a time

    Learn how to build bioinformatics pipelines with Nextflow, a powerful workflow management system for reproducible and scalable data analysis.


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  • Pseudoalignment for single cell RNA-seq with alevin-fry

    calendar Jul 28, 2025 · 4 min read · code single cell  ·
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    Pseudoalignment for single cell RNA-seq with alevin-fry

    Alevin-fry: pseudoalignment for computationally eficient single cell RNA-seq quantification


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Alfonso Saera Vila

Welcome to 'Love, DNA & Code' my blog about new bioinformatics tools, single-cell & spatial applications, AI, and more.
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Featured Posts

  • Visium HD cell segmentation with Bin2Cell
  • Single cell in Python: Scanpy and AnnData

Recent Posts

  • Autoencoders for Single Cell Data Analysis
  • BiocPy: Bioconductor in Python
  • Bringing the Tidyverse to Python: plotnine, siuba, and pyjanitor
  • Use uv for python and forget about anything else!
  • Building Your First Nextflow Pipeline: PART 4 - Polish your pipeline
  • Building Your First Nextflow Pipeline: PART 3 - Modularization & Configurable settings
  • Building Your First Nextflow Pipeline: PART 2 - Multiple Samples
  • Alignment or Pseudoalignment: Alevin-fry vs Cell Ranger comparison

Categories

BIOINFORMATICS 22 R 11 PYTHON 10 TECHNOLOGY 5 NEXTFLOW 4 CODE 2

Tags

SINGLE CELL 18 CODE 17 RNASEQ 10 BIOCONDUCTOR 6 DIMENSIONAL REDUCTION 4 PSEUDOALIGNMENT 4 AI 3 CELL SEGMENTATION 3 PSEUDOTIME 3 PYTHON 3 SPATIAL 3 DEEP LEARNING 2 PLOTS 2 RNA VELOCITY 2
All Tags
AI3 BIOCONDUCTOR6 CELL ANNOTATION1 CELL SEGMENTATION3 CHATGPT1 CODE17 DEEP LEARNING2 DIMENSIONAL REDUCTION4 INDEX1 LLM1 PHATE1 PLOTS2 PSEUDOALIGNMENT4 PSEUDOTIME3 PYTHON3 RNA VELOCITY2 RNASEQ10 SCANPY1 SCVELO1 SEURAT1 SINGLE CELL18 SPATIAL3 T-SNE1 TENSORFLOW1 TRAJECTORY ANALYSIS2 UMAP1 UV1
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Copyright © 2008–2025, Alfonso Saera plus the clarity & Hugo Authors

Copyright  COPYRIGHT © 2008–2025, ALFONSO SAERA PLUS THE CLARITY & HUGO AUTHORS. All Rights Reserved

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